Tesamorelin 10mg

Tesamorelin 10mg

GHRH analog · Visceral fat · Endogenous IGF-1 · Research Only

What is it and how does it work?

Tesamorelin is a stabilized synthetic analog of human growth hormone-releasing hormone (GHRH). It binds to the GHRH-R receptor on pituitary somatotrophs and stimulates pulsatile release of endogenous growth hormone, with documented increases in serum IGF-1 in clinical studies. The literature describes a preferential effect on abdominal visceral adipose tissue in cohorts with HIV-associated lipodystrophy.

Clinical evidence: Falutz et al. (NEJM 2007, PMID 17984164) reported a reduction in visceral fat in patients with HIV-associated lipodystrophy following treatment with 2 mg/day subcutaneous (SubQ) 15-20% for 26 weeks. Stanley et al. (JCI 2014, PMID 24911148) reported improvement in hepatic steatosis in nonalcoholic fatty liver disease. Research use only—no FDA-approved human use outside the specific indication of HIV-associated lipodystrophy (Egrifta).

Reconstitution and dosage

• Vial 10 mg lyophilized
• Bacteriostatic water: 2 ml
• Resulting concentration: 5,000 mcg/mL
• Per unit U-100: 50 mcg · verification: 5,000 ÷ 100 = 50 mcg/u ✓
• Conservation Refrigerate 2–8°C · Use within 28–30 days after reconstituting

Volume Conversion Chart (U-100 syringe)

Documented evidence

• Falutz J et al., NEJM 2007 (PMID 17984164) — Tesamorelin 2mg/day SubQ × 26 wks reduces visceral fat in HIV lipodystrophy
• Stanley TL et al., JCI 2014 (PMID 24911148) — Improvement of hepatic steatosis
• Adrian S et al., Clin Infect Dis 2018—Improvement in IGF-1 and Body Composition

Practical notes

• Via documented in clinical literature: SubQ once daily (typically night)
• The effect on IGF-1 is dose-dependent; literature reports IGF-1 monitoring every 6-12 weeks
• Research Stack: Tesamorelin + CJC/Ipa amplifies the GH axis; with BPC-157 for tissue regeneration

Contraindications and precautions

• For research use only. No human use approved by FDA outside of Egrifta® for HIV lipodystrophy. No established safety data for other uses. Not for human use.

Research material only. Not approved for human use by the FDA. This product is intended for scientific research purposes in controlled laboratory settings only. It is not a drug. Not for human or animal administration, therapeutic use, or diagnostic use.