{"id":1462,"date":"2026-05-27T09:59:01","date_gmt":"2026-05-27T14:59:01","guid":{"rendered":"https:\/\/elyxaminos.com\/producto\/igf-1-lr3-1mg\/"},"modified":"2026-07-27T09:32:46","modified_gmt":"2026-07-27T14:32:46","slug":"igf-1-lr3-1mg","status":"publish","type":"product","link":"https:\/\/elyxaminos.com\/en\/producto\/igf-1-lr3-1mg\/","title":{"rendered":"IGF-1 LR3 1mg"},"content":{"rendered":"
\n
\n\ud83d\udd39 In-depth Scientific Profile<\/summary>\n

IGF-1 LR3 (Long-R3 Insulin-like Growth Factor 1) es un an\u00e1logo sint\u00e9tico del IGF-1 humano descrito en la literatura como un p\u00e9ptido de 83 amino\u00e1cidos (PM ~9,200 Da) que combina dos modificaciones estrat\u00e9gicas:<\/span><\/p>\n

Modificaciones moleculares documentadas:<\/b><\/p>\n

    \n
  • Sustituci\u00f3n Arg\u00b3 \u2192 reduce afinidad por prote\u00ednas de uni\u00f3n IGFBP-3\/IGFBP-5 documentada en estudios bioqu\u00edmicos<\/span><\/li>\n
  • Extensi\u00f3n N-terminal de 13 amino\u00e1cidos derivados de hormona de crecimiento porcina<\/span><\/li>\n
  • Vida media plasm\u00e1tica extendida descrita en literatura (~20-30 horas vs. 12-15 min IGF-1 nativo)<\/span><\/li>\n
  • Afinidad por receptor IGF-1R conservada documentada en modelos in vitro<\/span><\/li>\n<\/ul>\n

    V\u00edas de se\u00f1alizaci\u00f3n descritas en literatura:<\/b><\/p>\n

      \n
    1. Receptor IGF-1R (tirosina quinasa):<\/b><\/li>\n<\/ol>\n
        \n
      • Activaci\u00f3n de IRS-1\/IRS-2 documentada en estudios bioqu\u00edmicos<\/span><\/li>\n
      • Cascada PI3K\/Akt\/mTORC1 reportada como v\u00eda principal de s\u00edntesis proteica<\/span><\/li>\n
      • MAPK\/ERK1\/2 asociado a proliferaci\u00f3n celular en literatura<\/span><\/li>\n<\/ul>\n
          \n
        1. Mecanismos celulares reportados (precl\u00ednicos):<\/b><\/li>\n<\/ol>\n
            \n
          • Activaci\u00f3n de c\u00e9lulas sat\u00e9lite musculares (Pax7+\/MyoD+) en modelos murinos<\/span><\/li>\n
          • Inhibici\u00f3n de FOXO\/atrofia proteol\u00edtica documentada en estudios in vitro<\/span><\/li>\n
          • Captaci\u00f3n de glucosa GLUT4-mediada en miocitos descrita en literatura<\/span><\/li>\n<\/ul>\n<\/details>\n
            \n\ud83d\udd2c DOCUMENTED SCIENTIFIC EVIDENCE<\/summary>\n

            La literatura cient\u00edfica documenta IGF-1 y sus an\u00e1logos en m\u00faltiples modelos experimentales:<\/span><\/p>\n

              \n
            • Tomas FM et al., Endocrinology 1993 (PMID 8462469):<\/b> an\u00e1logos LR3-IGF-1 en modelos de rata mostraron efectos anab\u00f3licos sobre s\u00edntesis proteica muscular<\/span><\/li>\n
            • Adams GR, Br J Sports Med 2002 (PMID 11916898):<\/b> revisi\u00f3n documenta papel de IGF-1 en hipertrofia muscular inducida por sobrecarga mec\u00e1nica<\/span><\/li>\n
            • Philippou A et al., In Vivo 2007 (PMID 17436567):<\/b> isoformas de IGF-1 en reparaci\u00f3n muscular post-ejercicio en modelos experimentales<\/span><\/li>\n
            • Frystyk J, Best Pract Res Clin Endocrinol Metab 2010 (PMID 20620540):<\/b> revisi\u00f3n sobre biolog\u00eda IGF-1 y an\u00e1logos sint\u00e9ticos<\/span><\/li>\n<\/ul>\n

              Research material only. No human FDA-approved use. All information is provided for educational purposes and reference to scientific literature.<\/i><\/p>\n<\/details>\n

              \n\u2697\ufe0f TECHNICAL SPECIFICATIONS<\/summary>\n
                \n
              • Identification:<\/b> IGF-1 LR3 (Long-R3 Insulin-like Growth Factor 1)<\/span><\/li>\n
              • Estructura:<\/b> 83 amino\u00e1cidos \u00b7 PM ~9,200 Da<\/span><\/li>\n
              • Modifications<\/b> Arg\u00b3 + extensi\u00f3n N-terminal de 13 aa<\/span><\/li>\n
              • Vial<\/b> 1 mg liofilizado<\/span><\/li>\n
              • Purity<\/b> >98% by HPLC<\/span><\/li>\n
              • Conservation<\/b> liofilizado refrigerado 2-8\u00b0C \u00b7 reconstituido usar en 28 d\u00edas<\/span><\/li>\n<\/ul>\n<\/details>\n
                \n\ud83d\udccb Recommended Use<\/summary>\n

                Material for scientific research purposes only.<\/b><\/p>\n

                Not for human consumption. No FDA approved human use. Information is provided for educational and reference purposes to published scientific literature.<\/span><\/p>\n<\/details>\n

                Research material only.<\/strong> This product is intended for scientific research in controlled laboratory settings only. It is not a drug. Not for human or animal use<\/strong>, not for diagnostic or therapeutic use.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"

                  \n
                • An\u00e1logo sint\u00e9tico de Factor de Crecimiento Insul\u00ednico Tipo 1 con extensi\u00f3n Long-R3 que prolonga su vida media plasm\u00e1tica para investigaci\u00f3n.<\/li>\n
                • Utilizado en estudios de proliferaci\u00f3n celular, miog\u00e9nesis e hipertrofia muscular en modelos experimentales.<\/li>\n
                • Apoya investigaci\u00f3n de v\u00edas PI3K\/Akt\/mTOR, diferenciaci\u00f3n de c\u00e9lulas sat\u00e9lite y reparaci\u00f3n tisular.<\/li>\n
                • Vial de 1 mg liofilizado \u00b7 compuesto de alta pureza \u00b7 uso exclusivo en investigaci\u00f3n cient\u00edfica.<\/li>\n<\/ul>","protected":false},"featured_media":1566,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[39,38,40],"product_tag":[],"class_list":{"0":"post-1462","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-aging","7":"product_cat-body-recomp","8":"product_cat-recovery","10":"first","11":"instock","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product\/1462","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/comments?post=1462"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/media\/1566"}],"wp:attachment":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/media?parent=1462"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_brand?post=1462"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_cat?post=1462"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_tag?post=1462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}