{"id":1456,"date":"2026-05-26T08:16:38","date_gmt":"2026-05-26T13:16:38","guid":{"rendered":"https:\/\/elyxaminos.com\/producto\/kisspeptin-10-10mg\/"},"modified":"2026-07-27T09:32:52","modified_gmt":"2026-07-27T14:32:52","slug":"kisspeptin-10-10mg","status":"publish","type":"product","link":"https:\/\/elyxaminos.com\/en\/producto\/kisspeptin-10-10mg\/","title":{"rendered":"Kisspeptin-10 10mg"},"content":{"rendered":"<section>\n<h2>Kisspeptin-10 10mg<\/h2>\n<p><strong>Activador HPG \u00b7 KISS1R agonista \u00b7 LH puls\u00e1til \u00b7 Research Only<\/strong><\/p>\n<h3>What is it and how does it work?<\/h3>\n<p>Kisspeptin-10 (KP-10) es el fragmento bioactivo C-terminal del producto del gen KISS1. Se une al receptor KISS1R (GPR54) en las neuronas GnRH del hipot\u00e1lamo, gatillando liberaci\u00f3n puls\u00e1til de GnRH que estimula secreci\u00f3n de LH y FSH en estudios neuroendocrinos. La literatura documenta efectos sobre LH\/testosterona en modelos animales y en ensayos cl\u00ednicos de investigaci\u00f3n exploratoria del eje HPG.<\/p>\n<p>Evidencia documentada: Chan YM et al. (JCEM 2011, PMID 21632807) reportaron que bolos IV de 0.24 nmol\/kg elevan LH con pico a 30-60 min en estudios farmacocin\u00e9ticos en hombres sanos como diagn\u00f3stico funcional del eje. George JT, Veldhuis JD et al. (Clin Endocrinol 2013, PMID 23153270) documentaron infusi\u00f3n de 4 mcg\/kg\/h \u00d7 11h en estudios exploratorios. Comninos AN et al. (JAMA Netw Open 2023, PMID 36735255) reportaron activaci\u00f3n cerebral sexual en investigaci\u00f3n funcional. Material de investigaci\u00f3n \u00fanicamente \u2014 sin uso humano aprobado por FDA.<\/p>\n<h3>Reconstitution and dosage<\/h3>\n<ul>\n<li><strong>Vial<\/strong> 10 mg lyophilized<\/li>\n<li><strong>Bacteriostatic water:<\/strong> 2 ml (standard rule: 1ml per 5mg)<\/li>\n<li><strong>Resulting concentration:<\/strong> 5,000 mcg\/mL<\/li>\n<li><strong>Per unit U-100:<\/strong> 50 mcg \u00b7 verification: 5,000 \u00f7 100 = 50 mcg\/u \u2713<\/li>\n<li><strong>Conservation<\/strong> Refrigerate at 2\u20138\u00b0C \u00b7 Use within 28\u201330 days<\/li>\n<li><strong>Performance<\/strong> Equivalent volume: 200 U-100 units per reconstituted vial<\/li>\n<\/ul>\n<h3>Volume Conversion Chart (U-100 syringe)<\/h3>\n<table border=\"1\" cellpadding=\"6\" cellspacing=\"0\" style=\"border-collapse: collapse;width: 100%\">\n<thead>\n<tr>\n<th style=\"background-color: #02042B;color: white;padding: 8px\">U-100 equivalent<\/th>\n<th style=\"background-color: #02042B;color: white;padding: 8px\">Volume<\/th>\n<th style=\"background-color: #02042B;color: white;padding: 8px\">Load (mcg)<\/th>\n<th style=\"background-color: #02042B;color: white;padding: 8px\">Verification<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td style=\"padding: 6px\">1 u<\/td>\n<td style=\"padding: 6px\">0.01 ml<\/td>\n<td style=\"padding: 6px\">50 mcg<\/td>\n<td style=\"padding: 6px\">1 u \u00d7 50 mcg = 50 mcg \u2713<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 6px\">2 u<\/td>\n<td style=\"padding: 6px\">0.02 ml<\/td>\n<td style=\"padding: 6px\">100 mcg<\/td>\n<td style=\"padding: 6px\">2 u \u00d7 50 mcg = 100 mcg \u2713<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 6px\">3 u<\/td>\n<td style=\"padding: 6px\">0.03 ml<\/td>\n<td style=\"padding: 6px\">150 mcg<\/td>\n<td style=\"padding: 6px\">3 u \u00d7 50 mcg = 150 mcg \u2713<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 6px\">4 u<\/td>\n<td style=\"padding: 6px\">0.04 ml<\/td>\n<td style=\"padding: 6px\">200 mcg<\/td>\n<td style=\"padding: 6px\">4 u \u00d7 50 mcg = 200 mcg \u2713<\/td>\n<\/tr>\n<tr>\n<td style=\"padding: 6px\">6 u<\/td>\n<td style=\"padding: 6px\">0.06 ml<\/td>\n<td style=\"padding: 6px\">300 mcg<\/td>\n<td style=\"padding: 6px\">6 u \u00d7 50 mcg = 300 mcg \u2713<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3>Documented evidence in research literature<\/h3>\n<details>\n<summary><strong>Evidencia cl\u00ednica exploratoria \u00b7 estimulaci\u00f3n puls\u00e1til LH<\/strong><\/summary>\n<ul>\n<li>Chan YM et al., JCEM 2011 (PMID 21632807): bolos IV de 0.24 nmol\/kg en hombres sanos \u2192 respuesta LH cuantificada como prueba funcional del eje HPG<\/li>\n<li>George JT, Veldhuis JD et al., Clin Endocrinol 2013 (PMID 23153270): infusi\u00f3n IV 4 mcg\/kg\/h \u00d7 11h en estudios exploratorios document\u00f3 elevaci\u00f3n LH y T y aumento de frecuencia de pulsos LH (0.6 \u2192 0.9 pulsos\/h) en investigaci\u00f3n<\/li>\n<li>Narayanaswamy et al. (PMC4507333): comparaci\u00f3n farmacocin\u00e9tica KP-10 vs KP-54 vs GnRH IV en investigaci\u00f3n funcional<\/li>\n<\/ul>\n<\/details>\n<details>\n<summary><strong>Evidencia exploratoria \u00b7 libido y activaci\u00f3n central<\/strong><\/summary>\n<ul>\n<li>Comninos AN et al., JAMA Netw Open 2023 (PMID 36735255): kisspeptin en investigaci\u00f3n de respuesta cerebral sexual \u2192 \u2191activaci\u00f3n de \u00e1reas relacionadas + \u2191tumescencia peneana 56% vs placebo en sujetos de investigaci\u00f3n<\/li>\n<li>Efecto sobre regiones cerebrales (fusiforme, corteza visual) documentado por fMRI en estudios de investigaci\u00f3n funcional<\/li>\n<\/ul>\n<\/details>\n<details>\n<summary><strong>Evidencia exploratoria \u00b7 administraci\u00f3n SubQ<\/strong><\/summary>\n<ul>\n<li>Jayasena CN et al., JCEM 2014: kisspeptin-54 SubQ en estudios farmacocin\u00e9ticos exploratorios \u2014 niveles plasm\u00e1ticos sostenidos vs IV<\/li>\n<li>R\u00e9gimen intermitente reportado: exposici\u00f3n continua de KISS1R desensibiliza el receptor v\u00eda \u03b2-arrestina en literatura mecan\u00edstica<\/li>\n<li>Vida media corta (~4 min IV para KP-10) prolongada por absorci\u00f3n SubQ en literatura<\/li>\n<\/ul>\n<\/details>\n<h3>Combinations reported in literature<\/h3>\n<ul>\n<li>KP-10 + HCG en literatura de investigaci\u00f3n PCT: v\u00edas complementarias documentadas \u2014 KP-10 est\u00edmulo central hipotal\u00e1mico; HCG mimetiza LH directo en c\u00e9lulas de Leydig.<\/li>\n<li>KP-10 + Tesamorelin: ejes neuroendocrinos independientes en investigaci\u00f3n \u2014 gonadal v\u00eda KISS1R\/GnRH + somatotr\u00f3pico v\u00eda GHRH.<\/li>\n<li>KP-10 + PT-141: literatura reporta v\u00edas centrales distintas \u2014 KP-10 modula \u00e1reas hipotal\u00e1micas y cortezas asociadas (Comninos 2023); PT-141 activa receptores MC4.<\/li>\n<li>KP-10 + CJC\/Ipamorelin en estudios de eje hormonal: optimizaci\u00f3n de ejes HPG + somatotr\u00f3pico en investigaci\u00f3n combinada.<\/li>\n<\/ul>\n<h3>Practical notes<\/h3>\n<ul>\n<li>Vial 10mg con reconstituci\u00f3n est\u00e1ndar (2 ml BW) genera 200 unidades U-100. Concentraci\u00f3n 5,000 mcg\/ml para dosificaci\u00f3n precisa con jeringa U-100.<\/li>\n<li>Literatura mecan\u00edstica documenta desensibilizaci\u00f3n de KISS1R con exposici\u00f3n continua v\u00eda \u03b2-arrestina (Jayasena et al.) \u2014 r\u00e9gimen puls\u00e1til\/intermitente es lo reportado en investigaci\u00f3n.<\/li>\n<\/ul>\n<h3>Contraindications and precautions<\/h3>\n<ul>\n<li>Material de investigaci\u00f3n \u00fanicamente. Sin uso humano aprobado por FDA. Sin datos de seguridad de uso cr\u00f3nico establecidos. No para uso humano.<\/li>\n<\/ul>\n<p><em><strong>Research material only. Not approved for human use by the FDA.<\/strong> This product is intended for scientific research purposes in controlled laboratory settings only. It is not a drug. Not for human or animal administration, therapeutic use, or diagnostic use.<\/em><\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p><strong>Activador HPG \u00b7 KISS1R agonista \u00b7 LH puls\u00e1til \u00b7 Research Only<\/strong><\/p>\n<ul>\n<li>Kisspeptin-10 (KP-10) es el fragmento bioactivo C-terminal del producto del gen KISS1.<\/li>\n<li>Se une al receptor KISS1R (GPR54) en las neuronas GnRH del hipot\u00e1lamo, gatillando liberaci\u00f3n puls\u00e1til de GnRH que estimula secreci\u00f3n de LH y FSH en estudios neuroendocrinos.<\/li>\n<li>La literatura documenta efectos sobre LH\/testosterona en modelos animales y en ensayos cl\u00ednicos de investigaci\u00f3n exploratoria del eje HPG.<\/li>\n<li><strong>Presentation<\/strong> 10 mg lyophilized lyophilized <strong>For research purposes only<\/strong><\/li>\n<\/ul>\n<p><!-- ELYX-CERT-BUTTONS:start --><\/p>\n<div style=\"display: flex;flex-wrap: wrap;gap: 8px;justify-content: center;margin-top: 16px;margin-bottom: 8px\">\n<a href=\"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/05\/KISS10_10MG_COA.pdf\" target=\"_blank\" rel=\"noreferrer\"><button style=\"display: flex;align-items: center;justify-content: center;background: linear-gradient(264.62deg, #02042B 11.77%, #0334D8 62.3%, #48DFE4 91.88%);padding: 12px 24px;border-radius: 50px;color: white;border: none;font-weight: bold;cursor: pointer;text-align: center;font-family: sans-serif;min-width: 130px\">Certificate of Analysis<\/button><\/a><br \/>\n<a href=\"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/05\/KISS10_10MG_ENDO.pdf\" target=\"_blank\" rel=\"noreferrer\"><button style=\"display: flex;align-items: center;justify-content: center;background: linear-gradient(264.62deg, #02042B 11.77%, #0334D8 62.3%, #48DFE4 91.88%);padding: 12px 24px;border-radius: 50px;color: white;border: none;font-weight: bold;cursor: pointer;text-align: center;font-family: sans-serif;min-width: 130px\">Endotoxins<\/button><\/a>\n<\/div>\n<p><!-- ELYX-CERT-BUTTONS:end --><\/p>","protected":false},"featured_media":1570,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[36],"product_tag":[],"class_list":{"0":"post-1456","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-testosterone-production","8":"first","9":"outofstock","10":"shipping-taxable","11":"purchasable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product\/1456","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/comments?post=1456"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/media\/1570"}],"wp:attachment":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/media?parent=1456"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_brand?post=1456"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_cat?post=1456"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_tag?post=1456"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}