{"id":1364,"date":"2026-05-11T22:17:36","date_gmt":"2026-05-12T03:17:36","guid":{"rendered":"https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/"},"modified":"2026-09-04T21:20:35","modified_gmt":"2026-09-05T02:20:35","slug":"tirzepatide-10mg","status":"publish","type":"product","link":"https:\/\/elyxaminos.com\/en\/producto\/tirzepatide-10mg\/","title":{"rendered":"Tirzepatide 10mg"},"content":{"rendered":"<section class=\"acordeon\">\n<details open=\"open\">\n<summary>\ud83d\udd39 IN-DEPTH SCIENTIFIC PROFILE<\/summary>\n<p><span style=\"font-weight: 400\">Tirzepatide is a modified-chain synthetic peptide representing the first dual agonist of the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. Its approximate molecular weight is 4,813 Da, with a 5-day half-life documented in the literature.<\/span><\/p>\n<p><b>Molecular design:<\/b><\/p>\n<ul>\n<li>Human GLP-1 derived basic scaffold<\/li>\n<li>39 amino acids with strategic modifications for dual receptor activity<\/li>\n<li>C20 acyl chain conjugated at specific position to extend half-life<\/li>\n<li>Serum albumin binding greater than 98%, which protects against enzymatic degradation<\/li>\n<\/ul>\n<p>The compound exhibits slightly unbalanced affinity toward GIP, a feature that appears responsible for the superior response versus pure GLP-1 agonists such as Semaglutide. The SURPASS-1 through SURPASS-5 phase 3 trials established its reference pharmacological profile.<\/p>\n<\/details>\n<details>\n<summary>\ud83d\udd2c MOLECULAR MECHANISM OF ACTION<\/summary>\n<p>Tirzepatide simultaneously activates two incretin pathways that normally operate in a coordinated manner in post-prandial physiology:<\/p>\n<p><b>GLP-1 Pathway:<\/b><\/p>\n<ul>\n<li>Increases glucose-dependent insulin secretion from pancreatic beta cells<\/li>\n<li>Suppresses glucagon secretion from alpha cells<\/li>\n<li>Delays gastric emptying, prolonging post-meal satiety<\/li>\n<li>Acts on hypothalamic nuclei (arcuate, paraventricular) modulating appetite<\/li>\n<\/ul>\n<p><b>GIP Pathway:<\/b><\/p>\n<ul>\n<li>Potentiates GLP-1-induced insulin secretion<\/li>\n<li>Modulates lipid metabolism in adipose tissue<\/li>\n<li>Improves nutrient partitioning toward oxidation vs storage<\/li>\n<li>Reduces low-grade inflammation in visceral adipose tissue<\/li>\n<\/ul>\n<p>The combination produces a documented synergistic effect: simultaneous activation of both receptors generates a greater metabolic response than the sum of each component separately, especially in terms of fat mass loss with relative preservation of lean mass.<\/p>\n<\/details>\n<details>\n<summary>\ud83e\uddea RESEARCH APPLICATIONS<\/summary>\n<p>The compound is widely investigated in the following contexts:<\/p>\n<ul>\n<li><b>Obesity Research:<\/b> SURMOUNT-1 through SURMOUNT-4 reported an average reduction in body weight of 15 to 22% at 72 weeks with doses of 10 to 15 mg\/week<\/li>\n<li><b>Type 2 diabetes<\/b> SURPASS-1 to SURPASS-5 established HbA1c reductions greater than those observed with Semaglutide<\/li>\n<li><b>Fatty liver disease<\/b> Phase 2 trials show significant reduction in liver lipid content<\/li>\n<li><b>Hypertension associated with obesity:<\/b> average reductions of 6 to 8 mmHg in systolic pressure<\/li>\n<li><b>Sleep apnea:<\/b> SURMOUNT-OSA showed improvement in the apnea-hypopnea index<\/li>\n<li><b>Cardiovascular Research:<\/b> SURPASS-CVOT ongoing evaluating major outcomes<\/li>\n<\/ul>\n<\/details>\n<details>\n<summary>\ud83e\uddea LABORATORY PREPARATION AND VOLUMETRIC CALCULATION<\/summary>\n<p><b>Reconstitution:<\/b><\/p>\n<p>Add 2 ml of bacteriostatic water to the 10 mg vial, letting the liquid slowly run down the inner wall of the vial. Homogenize with a gentle rotating motion, without shaking. Store refrigerated between 2 and 8\u00b0C.<\/p>\n<p>Resulting concentration: 5,000 mcg\/ml or 5 mg\/ml.<\/p>\n<p>A 10-mg vial provides 10 mg of the compound for research preparations at the specified concentration.<\/p>\n<\/details>\n<details>\n<summary>\u26a0\ufe0f SAFETY PROFILE DOCUMENTED IN THE LITERATURE<\/summary>\n<p>Adverse events commonly reported in clinical trial literature:<\/p>\n<ul>\n<li>Gastrointestinal: nausea (20-30%), diarrhea, constipation, dyspepsia<\/li>\n<li>Decreased appetite<\/li>\n<\/ul>\n<p>Less common but relevant events reported in the literature: acute pancreatitis (rare), hypersensitivity reactions, cholelithiasis associated with rapid weight loss.<\/p>\n<p><b>Documented contraindications in clinical literature:<\/b><\/p>\n<ul>\n<li>Personal or family history of medullary thyroid carcinoma<\/li>\n<li>Multiple Endocrine Neoplasia Type 2 (MEN 2) Syndrome<\/li>\n<li>Active pancreatitis or history of severe pancreatitis<\/li>\n<li>Pregnancy and breastfeeding<\/li>\n<\/ul>\n<p>Relevant documented drug interactions: delayed gastric emptying may alter the absorption of oral contraceptives and other gastric rate-sensitive drugs.<\/p>\n<\/details>\n<details>\n<summary>\ud83e\uddec STACKS AND COMBINATIONS IN RESEARCH<\/summary>\n<p>Tirzepatide is frequently studied alongside other compounds in research protocols depending on the study objective:<\/p>\n<ul>\n<li><b>Body recomposition<\/b> Tirzepatide + CJC No DAC + Ipamorelin, investigated for its association with lean mass preservation during fat loss<\/li>\n<li><b>Fatty liver disease<\/b> Tirzepatide + MOTS-C, studied for its association with mitochondrial lipid oxidation<\/li>\n<li><b>Metabolic Syndrome<\/b> Tirzepatide + Semaglutide in crossover studies (not simultaneous)<\/li>\n<li><b>Leather support<\/b> Tirzepatide + GHK-Cu, investigated in contexts of skin laxity associated with weight loss<\/li>\n<li><b>Pre-operative optimization<\/b> Low-dose tirzepatide in pre-bariatric optimization research<\/li>\n<\/ul>\n<\/details>\n<details>\n<summary>\ud83d\udcda SCIENTIFIC REFERENCES<\/summary>\n<ol>\n<li>Coskun T, Sloop KW, Loghin C, et al. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus. Mol Metab. 2018;18:3-14.<\/li>\n<li>Jastreboff AM, Aronne LJ, Ahmad NN, et al. Tirzepatide once weekly for the treatment of obesity. N Engl J Med. 2022;387(3):205-216.<\/li>\n<li>Fr\u00edas JP, Davies MJ, Rosenstock J, et al. Tirzepatide versus semaglutide once weekly in patients with type 2 diabetes. N Engl J Med. 2021;385(6):503-515.<\/li>\n<li>Rosenstock J, Wysham C, Fr\u00edas JP, et al. Efficacy and safety of tirzepatide in patients with type 2 diabetes (SURPASS-1). Lancet. 2021;398(10295):143-155.<\/li>\n<li>Malhotra A, Grunstein RR, Fietze I, et al. Tirzepatide for the treatment of obstructive sleep apnea and obesity (SURMOUNT-OSA). N Engl J Med. 2024;391(13):1193-1205.<\/li>\n<\/ol>\n<p><em>Product intended for scientific research purposes only. Not for human use or direct consumption. The buyer assumes full responsibility for handling the compound.<\/em><\/p>\n<\/details>\n<p style=\"margin-top:16px\"><strong>Research material only.<\/strong> This product is intended for scientific research in controlled laboratory settings only. It is not a drug. <strong>Not for human or animal use<\/strong>, not for diagnostic or therapeutic use.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<ul>\n<li>Dual GIP and GLP-1 receptor agonist for advanced metabolic research.<\/li>\n<li>Dual mechanism associated in the literature with central satiety, gastric emptying, and insulin sensitivity.<\/li>\n<li>10 mg vial, useful format for medium-duration research protocols.<\/li>\n<li>High-purity compound, intended exclusively for scientific research purposes.<\/li>\n<\/ul>\n<p><!-- ELYX-CERT-BUTTONS:start --><\/p>\n<div style=\"display: flex;flex-wrap: wrap;gap: 4px;justify-content: center;margin-top: 24px\">\n<a href=\"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/05\/TIRZE_10MG_COA.pdf\" target=\"_blank\" rel=\"noreferrer\"><button style=\"display: flex;align-items: center;justify-content: center;background: linear-gradient(264.62deg, #02042B 11.77%, #0334D8 62.3%, #48DFE4 91.88%);padding: 15px 30px;border-radius: 50px;color: white;border: none;font-weight: bold;cursor: pointer;text-align: center;font-family: sans-serif;min-width: 150px\">Certificate of Analysis<\/button><\/a><br \/>\n<a href=\"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/05\/TIRZE_10MG_ENDO.pdf\" target=\"_blank\" rel=\"noreferrer\"><button style=\"display: flex;align-items: center;justify-content: center;background: linear-gradient(264.62deg, #02042B 11.77%, #0334D8 62.3%, #48DFE4 91.88%);padding: 15px 30px;border-radius: 50px;color: white;border: none;font-weight: bold;cursor: pointer;text-align: center;font-family: sans-serif;min-width: 150px\">Endotoxins<\/button><\/a>\n<\/div>\n<p><!-- ELYX-CERT-BUTTONS:end --><\/p>","protected":false},"featured_media":1927,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[37,38,41],"product_tag":[49],"class_list":["post-1364","product","type-product","status-publish","has-post-thumbnail","product_cat-fat-loss","product_cat-body-recomp","product_cat-metabolic-health","product_tag-destacados","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tirzepatide 10mg - Elyxaminos<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/elyxaminos.com\/en\/product\/tirzepatide-10mg\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tirzepatide 10mg - Elyxaminos\" \/>\n<meta property=\"og:description\" content=\"Agonista dual de los receptores GIP y GLP-1 para investigaci\u00f3n metab\u00f3lica avanzada. Mecanismo doble que en la literatura se asocia con saciedad central, vaciado g\u00e1strico y sensibilidad a la insulina. Vial de 10 mg, formato \u00fatil para protocolos de investigaci\u00f3n de duraci\u00f3n intermedia. Compuesto de alta pureza, destinado exclusivamente a fines de investigaci\u00f3n cient\u00edfica.  COA Endotoxins\" \/>\n<meta property=\"og:url\" content=\"https:\/\/elyxaminos.com\/en\/product\/tirzepatide-10mg\/\" \/>\n<meta property=\"og:site_name\" content=\"Elyxaminos\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-05T02:20:35+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/05\/Tirzepatide-10mg-front.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1920\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/tirzepatide-10mg\\\/\",\"url\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/tirzepatide-10mg\\\/\",\"name\":\"Tirzepatide 10mg - Elyxaminos\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/tirzepatide-10mg\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/tirzepatide-10mg\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/elyxaminos.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/Tirzepatide-10mg-v3.webp\",\"datePublished\":\"2026-05-12T03:17:36+00:00\",\"dateModified\":\"2026-09-05T02:20:35+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/tirzepatide-10mg\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/tirzepatide-10mg\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/tirzepatide-10mg\\\/#primaryimage\",\"url\":\"https:\\\/\\\/elyxaminos.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/Tirzepatide-10mg-v3.webp\",\"contentUrl\":\"https:\\\/\\\/elyxaminos.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/Tirzepatide-10mg-v3.webp\",\"width\":1920,\"height\":1920},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/tirzepatide-10mg\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Inicio\",\"item\":\"https:\\\/\\\/elyxaminos.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Tienda\",\"item\":\"https:\\\/\\\/elyxaminos.com\\\/tienda\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Tirzepatide 10mg\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/#website\",\"url\":\"https:\\\/\\\/elyxaminos.com\\\/\",\"name\":\"Elyxaminos\",\"description\":\"Tu tienda de confianza\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/elyxaminos.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Tirzepatide 10 mg \u2013 Elyxaminos","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/elyxaminos.com\/en\/product\/tirzepatide-10mg\/","og_locale":"en_US","og_type":"article","og_title":"Tirzepatide 10mg - Elyxaminos","og_description":"Agonista dual de los receptores GIP y GLP-1 para investigaci\u00f3n metab\u00f3lica avanzada. Mecanismo doble que en la literatura se asocia con saciedad central, vaciado g\u00e1strico y sensibilidad a la insulina. Vial de 10 mg, formato \u00fatil para protocolos de investigaci\u00f3n de duraci\u00f3n intermedia. Compuesto de alta pureza, destinado exclusivamente a fines de investigaci\u00f3n cient\u00edfica.  COA Endotoxins","og_url":"https:\/\/elyxaminos.com\/en\/product\/tirzepatide-10mg\/","og_site_name":"Elyxaminos","article_modified_time":"2026-09-05T02:20:35+00:00","og_image":[{"width":1920,"height":1920,"url":"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/05\/Tirzepatide-10mg-front.webp","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/","url":"https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/","name":"Tirzepatide 10 mg \u2013 Elyxaminos","isPartOf":{"@id":"https:\/\/elyxaminos.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/#primaryimage"},"image":{"@id":"https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/#primaryimage"},"thumbnailUrl":"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/09\/Tirzepatide-10mg-v3.webp","datePublished":"2026-05-12T03:17:36+00:00","dateModified":"2026-09-05T02:20:35+00:00","breadcrumb":{"@id":"https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/#primaryimage","url":"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/09\/Tirzepatide-10mg-v3.webp","contentUrl":"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/09\/Tirzepatide-10mg-v3.webp","width":1920,"height":1920},{"@type":"BreadcrumbList","@id":"https:\/\/elyxaminos.com\/producto\/tirzepatide-10mg\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Inicio","item":"https:\/\/elyxaminos.com\/"},{"@type":"ListItem","position":2,"name":"Tienda","item":"https:\/\/elyxaminos.com\/tienda\/"},{"@type":"ListItem","position":3,"name":"Tirzepatide 10mg"}]},{"@type":"WebSite","@id":"https:\/\/elyxaminos.com\/#website","url":"https:\/\/elyxaminos.com\/","name":"Elyxaminos","description":"Your trusted store","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/elyxaminos.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product\/1364","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/comments?post=1364"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/media\/1927"}],"wp:attachment":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/media?parent=1364"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_brand?post=1364"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_cat?post=1364"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_tag?post=1364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}