{"id":1359,"date":"2026-05-11T22:17:32","date_gmt":"2026-05-12T03:17:32","guid":{"rendered":"https:\/\/elyxaminos.com\/producto\/semax-10mg\/"},"modified":"2026-09-04T21:45:23","modified_gmt":"2026-09-05T02:45:23","slug":"semax-10mg","status":"publish","type":"product","link":"https:\/\/elyxaminos.com\/en\/producto\/semax-10mg\/","title":{"rendered":"Semax 10mg"},"content":{"rendered":"
\n
\n\ud83d\udd39 IN-DEPTH SCIENTIFIC PROFILE<\/summary>\n

Semax is a synthetic heptapeptide derived from the 4-10 region of adrenocorticotropic hormone (ACTH), with a terminal Pro-Gly-Pro modification that significantly extends its half-life. It was developed at the Institute of Molecular Biology of the Russian Academy of Sciences in the 80s and is one of the most-studied peptide nootropics in the scientific literature.<\/p>\n

Molecular structure:<\/b><\/p>\n

    \n
  • Met-Glu-His-Phe-Pro-Gly-Pro<\/li>\n
  • Molecular weight: 813.9 Da<\/li>\n
  • Average half-life: 60 to 90 minutes (significantly longer than the original ACTH 4-10)<\/li>\n
  • Valid routes of administration: intranasal and subcutaneous<\/li>\n<\/ul>\n

    Unlike full-length ACTH, Semax lacks activity on the adrenal cortex, eliminating effects on cortisol and aldosterone and leaving only the neuroactive action.<\/p>\n<\/details>\n

    \n\ud83d\udd2c MOLECULAR MECHANISM OF ACTION<\/summary>\n
      \n
    • Increased BDNF and NGF:<\/b> Semax stimulates the brain's expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), key factors for synaptic plasticity.<\/li>\n
    • Neurotransmitter Modulation<\/b> increases dopaminergic and serotonergic tone in specific regions, without causing massive release<\/li>\n
    • Inhibition of enkephalins and endorphins:<\/b> protect these endogenous opioids from enzymatic degradation<\/li>\n
    • Neuroprotective action<\/b> reduce neuronal damage in models of cerebral ischemia<\/li>\n
    • Melanocortin receptor activation<\/b> contributes to the regulation of alertness and attention<\/li>\n<\/ul>\n<\/details>\n
      \n\ud83e\uddea RESEARCH APPLICATIONS<\/summary>\n
        \n
      • Post-ischemic stroke recovery (clinical use approved in Russia)<\/li>\n
      • Memory and learning enhancement in healthy adults<\/li>\n
      • Attention deficit disorder (ADHD)<\/li>\n
      • Cognitive fatigue and burnout<\/li>\n
      • Post-traumatic brain injury recovery<\/li>\n
      • Research in mild cognitive impairment and early dementia<\/li>\n
      • Performance improvement in demanding cognitive tasks<\/li>\n<\/ul>\n<\/details>\n
        \n\ud83d\udc89 RECONSTITUTION PROTOCOL<\/summary>\n

        Reconstitution:<\/b> add 2 ml of bacteriostatic water to the 10 mg vial. Concentration: 5,000 mcg\/ml.<\/p>\n

        Routes of administration:<\/b><\/p>\n

          \n
        • Subcutaneous<\/b> standard route of administration for Elyx Aminos compounds.<\/li>\n
        • Note:<\/b> the literature also describes the intranasal route for its CNS bioavailability; it is documented here as a bibliographic reference.<\/li>\n<\/ul>\n<\/details>\n
          \n\u26a0\ufe0f SAFETY CONSIDERATIONS<\/summary>\n

          Excellent safety profile documented in decades of Russian clinical use. Rare adverse events: local nasal irritation with prolonged intranasal use, mild headache, insomnia if administered late in the day.<\/p>\n

          Avoid in patients with bipolar disorder or active psychosis due to its dopaminergic action. Do not combine with MAOIs or dopamine reuptake inhibitors without supervision.<\/p>\n<\/details>\n

          \n\ud83e\uddec POPULAR STACK AND COMBINATIONS<\/summary>\n
            \n
          • Cognition + emotional stability<\/b> Semax + Selank (classic Russian combination)<\/li>\n
          • Neurological Recovery<\/b> Semax + NAD+ for cerebral mitochondrial support<\/li>\n
          • Integral burnout:<\/b> Semax + Selank + DSIP for focus, calm, and sleep<\/li>\n<\/ul>\n<\/details>\n
            \n\ud83d\udcda SCIENTIFIC REFERENCES<\/summary>\n
              \n
            1. Asmarin IP, Nezavibatko VN, Myasoedov NF, et al. A nootropic adrenocorticotropin analog 4-10-Semax: 15 years experience in development and study. J Higher Nervous Activity I P Pavlov. 1997;47(2):420-430.<\/li>\n
            2. Dolotov OV, Karpenko EA, Inozemtseva LS, et al. Semax, an analog of adrenocorticotropin (4-10), specifically binds and increases brain-derived neurotrophic factor protein levels in the rat basal forebrain. J Neurochem. 2006;97(Suppl 1):82-86.<\/li>\n
            3. Shadrina MI, Dolotov OV, Grivennikov IA, et al. Rapid induction of neurotrophin mRNAs in rat glial cell cultures by Semax, an adrenocorticotropic hormone analog. Neurosci Lett. 2001;308(2):115-118.<\/li>\n<\/ol>\n<\/details>\n

              Research material only.<\/strong> This product is intended for scientific research in controlled laboratory settings only. It is not a drug. Not for human or animal use<\/strong>, not for diagnostic or therapeutic use.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"

                \n
              • Synthetic nootropic heptapeptide derived from ACTH (4-10) fragmentation.<\/li>\n
              • Stimulates BDNF and NGF, key trophic factors for neuronal plasticity.<\/li>\n
              • Researched in cognition, post-ischemic recovery, and attention disorders.<\/li>\n
              • Originally developed in Russia, widely used in neurological research.<\/li>\n<\/ul>","protected":false},"featured_media":1939,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[46],"product_tag":[49],"class_list":["post-1359","product","type-product","status-publish","has-post-thumbnail","product_cat-cognicion","product_tag-destacados","first","instock","shipping-taxable","purchasable","product-type-simple"],"yoast_head":"\nSemax 10mg - Elyxaminos<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/elyxaminos.com\/en\/product\/semax-10mg\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Semax 10mg - Elyxaminos\" \/>\n<meta property=\"og:description\" content=\"Heptap\u00e9ptido nootr\u00f3pico sint\u00e9tico derivado de la fragmentaci\u00f3n de la ACTH (4-10). Estimula BDNF y NGF, factores tr\u00f3ficos clave para plasticidad neuronal. Investigado en cognici\u00f3n, recuperaci\u00f3n post-isqu\u00e9mica y trastornos de atenci\u00f3n. Originalmente desarrollado en Rusia, ampliamente utilizado en investigaci\u00f3n neurol\u00f3gica.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/elyxaminos.com\/en\/product\/semax-10mg\/\" \/>\n<meta property=\"og:site_name\" content=\"Elyxaminos\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-05T02:45:23+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/05\/Semax-10mg-front-bluecap.webp\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1920\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/semax-10mg\\\/\",\"url\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/semax-10mg\\\/\",\"name\":\"Semax 10mg - Elyxaminos\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/semax-10mg\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/semax-10mg\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/elyxaminos.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/Semax-10mg-v3.webp\",\"datePublished\":\"2026-05-12T03:17:32+00:00\",\"dateModified\":\"2026-09-05T02:45:23+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/semax-10mg\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/semax-10mg\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/semax-10mg\\\/#primaryimage\",\"url\":\"https:\\\/\\\/elyxaminos.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/Semax-10mg-v3.webp\",\"contentUrl\":\"https:\\\/\\\/elyxaminos.com\\\/wp-content\\\/uploads\\\/2026\\\/09\\\/Semax-10mg-v3.webp\",\"width\":1920,\"height\":1920},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/producto\\\/semax-10mg\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Inicio\",\"item\":\"https:\\\/\\\/elyxaminos.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Tienda\",\"item\":\"https:\\\/\\\/elyxaminos.com\\\/tienda\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Semax 10mg\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/elyxaminos.com\\\/#website\",\"url\":\"https:\\\/\\\/elyxaminos.com\\\/\",\"name\":\"Elyxaminos\",\"description\":\"Tu tienda de confianza\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/elyxaminos.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Semax 10mg - Elyxaminos","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/elyxaminos.com\/en\/product\/semax-10mg\/","og_locale":"en_US","og_type":"article","og_title":"Semax 10mg - Elyxaminos","og_description":"Heptap\u00e9ptido nootr\u00f3pico sint\u00e9tico derivado de la fragmentaci\u00f3n de la ACTH (4-10). Estimula BDNF y NGF, factores tr\u00f3ficos clave para plasticidad neuronal. Investigado en cognici\u00f3n, recuperaci\u00f3n post-isqu\u00e9mica y trastornos de atenci\u00f3n. Originalmente desarrollado en Rusia, ampliamente utilizado en investigaci\u00f3n neurol\u00f3gica.","og_url":"https:\/\/elyxaminos.com\/en\/product\/semax-10mg\/","og_site_name":"Elyxaminos","article_modified_time":"2026-09-05T02:45:23+00:00","og_image":[{"width":1920,"height":1920,"url":"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/05\/Semax-10mg-front-bluecap.webp","type":"image\/png"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/elyxaminos.com\/producto\/semax-10mg\/","url":"https:\/\/elyxaminos.com\/producto\/semax-10mg\/","name":"Semax 10mg - Elyxaminos","isPartOf":{"@id":"https:\/\/elyxaminos.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/elyxaminos.com\/producto\/semax-10mg\/#primaryimage"},"image":{"@id":"https:\/\/elyxaminos.com\/producto\/semax-10mg\/#primaryimage"},"thumbnailUrl":"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/09\/Semax-10mg-v3.webp","datePublished":"2026-05-12T03:17:32+00:00","dateModified":"2026-09-05T02:45:23+00:00","breadcrumb":{"@id":"https:\/\/elyxaminos.com\/producto\/semax-10mg\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/elyxaminos.com\/producto\/semax-10mg\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/elyxaminos.com\/producto\/semax-10mg\/#primaryimage","url":"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/09\/Semax-10mg-v3.webp","contentUrl":"https:\/\/elyxaminos.com\/wp-content\/uploads\/2026\/09\/Semax-10mg-v3.webp","width":1920,"height":1920},{"@type":"BreadcrumbList","@id":"https:\/\/elyxaminos.com\/producto\/semax-10mg\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Inicio","item":"https:\/\/elyxaminos.com\/"},{"@type":"ListItem","position":2,"name":"Tienda","item":"https:\/\/elyxaminos.com\/tienda\/"},{"@type":"ListItem","position":3,"name":"Semax 10mg"}]},{"@type":"WebSite","@id":"https:\/\/elyxaminos.com\/#website","url":"https:\/\/elyxaminos.com\/","name":"Elyxaminos","description":"Your trusted store","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/elyxaminos.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product\/1359","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/comments?post=1359"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/media\/1939"}],"wp:attachment":[{"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/media?parent=1359"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_brand?post=1359"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_cat?post=1359"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/elyxaminos.com\/en\/wp-json\/wp\/v2\/product_tag?post=1359"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}