Epithalon 10mg

Epithalon (also spelled Epitalon) is a synthetic tetrapeptide of sequence Ala-Glu-Asp-Gly (AEDG), presented as a 10 mg lyophilized research vial.

Signaling pathways documented in the literature:

• Telomerase activation (hTERT): Cellular models document induction of telomerase activity and telomere elongation in cultured human fibroblasts
• Circadian modulation: Preclinical rodent studies describe normalization of melatonin secretion and circadian rhythm
• Gene Regulation / Chromatin Experimental literature reports effects on gene expression and chromatin structure (perinuclear heterochromatin).

• Khavinson VK et al., Neuro Endocrinol Lett 2003 (PMID 14523363): Epithalon in models of cellular aging and telomerase activation
• Anisimov VN et al., Mech Ageing Dev 2003 (PMID 12782392): Epithalon in murine models of longevity and carcinogenesis
• Khavinson VK, Bull Exp Biol Med 2002 (PMID 12937682): Effects of the tetrapeptide on telomerase activity in human cell cultures

Research material only. No FDA-approved human use. All information is provided for educational and scientific literature reference purposes.

• Identification: Epithalon (AEDG) — tetrapeptide Ala-Glu-Asp-Gly
• Presentation 10 mg lyophilized per vial
• Purity >98% by HPLC
• Laboratory reconstitution: 2 mL of bacteriostatic water → 5,000 mcg/mL
• Conservation Lyophilized refrigerated 2-8°C · protect from light · use within 28 days after reconstitution

Material intended exclusively for scientific research.

Not for human consumption. No FDA-approved human use. Information is provided for educational and reference purposes to the published scientific literature.