GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a tripeptide with applications ranging from skin regeneration to wound repair, positioning itself at the intersection of aesthetic and wellness clinics.
What Is GHK-Cu?
Tripeptide (Glycine-Histidine-Lysine) with high copper affinity, naturally present in plasma, saliva and urine. Identified in the 1970s.
Mechanisms of Action:
1. Estimulación de Colágeno
Increases collagen production by up to 70%, outperforming vitamin C (~50%) and retinoic acid (~40%). Copper is a cofactor for lysyl oxidase/hydroxylase.
2. Modulación de MMPs
Dual effect: stimulates MMPs to clear damaged tissue and boosts decorin to protect existing collagen.
3. Regulación Génica
Modulates thousands of genes toward a more youthful expression profile (shown by microarrays).
Evidencia Clínica
| Study | Detalles | Resultado |
|---|---|---|
| Crema facial 12 semanas | 71 mujeres, tópica diaria | Mejora densidad, espesor, reducción arrugas |
| Colágeno vs. competidores | In vitro | 70% GHK-Cu vs 50% Vit C vs 40% retinoico |
| Cicatrización | Modelos preclínicos | Cierre acelerado, mayor angiogénesis |
| Antiinflamatorio | Marcadores | Reducción significativa TNF-α |
| Hair growth | Preliminares | Estimulación folículos pilosos |
| Penetración cutánea | Topic | 2.53-4.61% depending on formulation |
Applications:
- Anti-aging Collagen and elastin for wrinkles and firmness.
- Post-procedimiento: Recovery after laser, microneedling and peels.
- Cicatrices: Remodelación de tejido cicatricial.
- Cabello: Estimulación de folículos pilosos.
| Way | Uso | Considerations: |
|---|---|---|
| Topic | Facial anti-ageing | Penetración 2-5% |
| Subcutaneous | Systemic research | Documented in the research literature |
| Mesoterapia | Clinical application | With other aesthetic peptides |
Presentación Elyx: GHK-Cu 50mg, pureza 99.631%.
Conclusion
GHK-Cu is one of the most versatile peptides, spanning aesthetic dermatology to longevity. 99.631% purity verified by Freedom Diagnostics Testing.
ELYX AMINOS
Premium Research Compounds · Verified Purity · Rigorous Science
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Miami, Florida, USA.
